منابع مشابه
Proton channels.
The structure of Nafion, the polymer electrolyte membrane used in some fuel cells, has been extensively debated over recent decades. Now, a newly proposed model reveals the nanoscale arrangement that could explain the excellent transport properties of the material. Transport is a major source of pollution in cities. As a result, the development of cars and buses which generate low or negligible...
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M2 of the influenza virus is an intriguing transmembrane protein that forms a minuscule proton channel in the viral envelope. Its recognized function is to equilibrate pH across the viral membrane during cell entry and across the trans-Golgi membrane of infected cells during viral maturation. It is vital for viral replication and it is a target for the anti-influenza drugs, amantadine and riman...
متن کاملInfluenza virus proton channels.
The M2 ion channel proteins of influenza A and B viruses are essential to viral replication. The two ion channels share a common motif, HXXXW, that is responsible for proton selectivity and activation. The ion channel for the influenza A virus, but not influenza B virus, is inhibited by the antiviral drug amantadine and amantadine-resistant escape mutants form in treated influenza A patients. T...
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A battle is raging over the molecular identity of the voltage-gated, H -selective conductance that has been recorded in activated and/or depolarized phagocytes. Having stepped out of this arena, we feel uncommitted to any particular viewpoint and hope to be able to provide below an unbiased opinion of what we feel has been established unambiguously, and what requires additional confirmation bef...
متن کاملProton Channels from Solid - State
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ژورنال
عنوان ژورنال: Nature Materials
سال: 2008
ISSN: 1476-1122,1476-4660
DOI: 10.1038/nmat2091